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Last year I have traveled to Madagascar. It is the biggest island in the Indian Ocean and the biggest island in the whole world. The flora and fauna are astonishing there, as well as the range of different bacteria and infections one can catch there. Before the trip I have taken Quinine to protect me from malaria as it is a very nasty disease to catch. I started on Quinine two days before the departure and continued for several days after I came back. I believe it's due to Quinine that I have not contracted malaria, neither have I had any side effects connected with taking the medication. It is very important that such vital drugs that help prevent life-threatening diseases do not create major difficulties for people who have no other way out but taking them.

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What your husband should ask about (and this would have to be within the conventional health system) is whether he can take a course of primaquine.

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The most common toxic effects that have been identified are nausea, vomiting, anorexia, and dizziness; these are probably due, in many patients, to acute malaria rather than to the drugs.

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However, the proportions of patients with nausea, vomiting, and liver enlargement at enrollment were similar in the two groups (data not shown).

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In these cases, clinical differentiation and decision making will be important; however, the clinician should have a low threshold for including the possible presence of P falciparum in the treatment considerations.

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